Health Library

Our Health Library information does not replace the advice of a doctor. The health library is made available to assist our patients to learn more about their health.

morphine

Pronunciation: MOR feen

Brand: Arymo ER, Kadian, MorphaBond ER, MS Contin

Morphine Sulfate

slide 1 of 55, Morphine Sulfate,

15 mg, round, white, imprinted with 54 733

Image of Morphine Sulfate
slide 1 of 55
    

Morphine Sulfate ER

slide 2 of 55, Morphine Sulfate ER,

30 mg/8 to 12 hr, round, purple, imprinted with M, MS 30

Image of Morphine Sulfate ER
slide 2 of 55
    

Morphine Sulfate ER

slide 3 of 55, Morphine Sulfate ER,

60 mg/8 to 12 hr, round, orange, imprinted with M, MS 60

Image of Morphine Sulfate ER
slide 3 of 55
    

Morphine Sulfate ER

slide 4 of 55, Morphine Sulfate ER,

100 mg/8 to 12 hr, round, gray, imprinted with M, MS 100

Image of Morphine Sulfate ER
slide 4 of 55
    

Morphine Sulfate ER

slide 5 of 55, Morphine Sulfate ER,

15 mg/12 hr, round, blue, imprinted with 15, M inside square

Image of Morphine Sulfate ER
slide 5 of 55
    

Morphine Sulfate ER

slide 6 of 55, Morphine Sulfate ER,

200 mg/8 to 12 hr, oblong, green, imprinted with 200, M inside square

Image of Morphine Sulfate ER
slide 6 of 55
    

Morphine Sulfate ER

slide 7 of 55, Morphine Sulfate ER,

30 mg/12 hr, round, purple, imprinted with 30, M inside square

Image of Morphine Sulfate ER
slide 7 of 55
    

Morphine Sulfate ER

slide 8 of 55, Morphine Sulfate ER,

60 mg/12 hours, round, orange, imprinted with 60, M inside square

Image of Morphine Sulfate ER
slide 8 of 55
    

Morphine Sulfate ER

slide 9 of 55, Morphine Sulfate ER,

100 mg/12 hours, round, gray, imprinted with 100, M inside square

Image of Morphine Sulfate ER
slide 9 of 55
    

Morphine Sulfate ER

slide 10 of 55, Morphine Sulfate ER,

15 mg/8 to 12 hr, round, blue, imprinted with ABG, 15

Image of Morphine Sulfate ER
slide 10 of 55
    

Morphine Sulfate ER

slide 11 of 55, Morphine Sulfate ER,

30 mg/8 to 12 hr, round, purple, imprinted with ABG, 30

Image of Morphine Sulfate ER
slide 11 of 55
    

Morphine Sulfate ER

slide 12 of 55, Morphine Sulfate ER,

60 mg/8 to 12 hr, round, orange, imprinted with ABG, 60

Image of Morphine Sulfate ER
slide 12 of 55
    

Morphine Sulfate ER

slide 13 of 55, Morphine Sulfate ER,

100 mg/8 to 12 hr, round, gray, imprinted with ABG, 100

Image of Morphine Sulfate ER
slide 13 of 55
    

Morphine Sulfate ER

slide 14 of 55, Morphine Sulfate ER,

15 mg/12 hr, round, blue, imprinted with 15, E652

Image of Morphine Sulfate ER
slide 14 of 55
    

Morphine Sulfate ER

slide 15 of 55, Morphine Sulfate ER,

30 mg/12 hr, round, green, imprinted with 30, E653

Image of Morphine Sulfate ER
slide 15 of 55
    

Morphine Sulfate ER

slide 16 of 55, Morphine Sulfate ER,

60 mg/12 hours, oblong, orange, imprinted with 60, E655

Image of Morphine Sulfate ER
slide 16 of 55
    

Morphine Sulfate ER

slide 17 of 55, Morphine Sulfate ER,

100 mg/12 hours, oblong, blue, imprinted with 100, E658

Image of Morphine Sulfate ER
slide 17 of 55
    

Morphine Sulfate ER

slide 18 of 55, Morphine Sulfate ER,

200 mg/8 to 12 hr, oval, green, imprinted with E659, 200

Image of Morphine Sulfate ER
slide 18 of 55
    

AVINza

slide 19 of 55, AVINza,

120 mg/24 hours, capsule, blue/white, imprinted with AVINZA, 120mg 508

Image of AVINza
slide 19 of 55
    

AVINza

slide 20 of 55, AVINza,

30 mg/24 hours, capsule, white/yellow, imprinted with AVINZA, 30 mg 505

Image of AVINza
slide 20 of 55
    

AVINza

slide 21 of 55, AVINza,

45 mg/24 hours, capsule, blue/white, imprinted with AVINZA, 45 MG 509

Image of AVINza
slide 21 of 55
    

AVINza

slide 22 of 55, AVINza,

60 mg/24 hours, capsule, blue/white, imprinted with AVINZA, 60 mg 506

Image of AVINza
slide 22 of 55
    

AVINza

slide 23 of 55, AVINza,

90 mg/24 hours, capsule, red/white, imprinted with AVINZA, 90 mg 507

Image of AVINza
slide 23 of 55
    

Kadian

slide 24 of 55, Kadian,

100 mg/12 to 24 hr, capsule, green, imprinted with KADIAN, 100 mg

Image of Kadian
slide 24 of 55
    

Morphine Sulfate ER

slide 25 of 55, Morphine Sulfate ER,

30 mg/12 to 24 hr, capsule, blue, imprinted with KADIAN, 30 mg

Image of Morphine Sulfate ER
slide 25 of 55
    

Kadian

slide 26 of 55, Kadian,

50 mg/12 to 24 hr, capsule, blue, imprinted with KADIAN, 50 mg

Image of Kadian
slide 26 of 55
    

Morphine Sulfate ER

slide 27 of 55, Morphine Sulfate ER,

60 mg/12 to 24 hr, capsule, pink, imprinted with KADIAN, 60 mg

Image of Morphine Sulfate ER
slide 27 of 55
    

Morphine Sulfate ER

slide 28 of 55, Morphine Sulfate ER,

80 mg/12 to 24 hr, capsule, orange, imprinted with KADIAN, 80 mg

Image of Morphine Sulfate ER
slide 28 of 55
    

Morphine Sulfate ER

slide 29 of 55, Morphine Sulfate ER,

15 mg/12 hr, oval, green, imprinted with 15, E

Image of Morphine Sulfate ER
slide 29 of 55
    

Morphine Sulfate

slide 30 of 55, Morphine Sulfate,

15 mg, round, white, imprinted with 54 733

Image of Morphine Sulfate
slide 30 of 55
    

Morphine Sulfate

slide 31 of 55, Morphine Sulfate,

30 mg, round, white/blue specks, imprinted with 54 262

Image of Morphine Sulfate
slide 31 of 55
    

Morphine Sulfate ER

slide 32 of 55, Morphine Sulfate ER,

60 mg/12 hours, oval, white, imprinted with 60, E

Image of Morphine Sulfate ER
slide 32 of 55
    

Morphine Sulfate ER

slide 33 of 55, Morphine Sulfate ER,

100 mg/12 hours, round, gray, imprinted with ABG, 100

Image of Morphine Sulfate ER
slide 33 of 55
    

Morphine Sulfate ER

slide 34 of 55, Morphine Sulfate ER,

15 mg/12 hr, round, blue, imprinted with ABG, 15

Image of Morphine Sulfate ER
slide 34 of 55
    

Morphine Sulfate ER

slide 35 of 55, Morphine Sulfate ER,

30 mg/12 hr, round, pink, imprinted with ABG, 30

Image of Morphine Sulfate ER
slide 35 of 55
    

Morphine Sulfate ER

slide 36 of 55, Morphine Sulfate ER,

60 mg/12 hours, round, pink, imprinted with ABG, 60

Image of Morphine Sulfate ER
slide 36 of 55
    

Morphine IR

slide 37 of 55, Morphine IR,

15 mg, round, brown, imprinted with 15, ETH

Image of Morphine IR
slide 37 of 55
    

Morphine IR

slide 38 of 55, Morphine IR,

30 mg, oblong, brown, imprinted with 30, ETHEX

Image of Morphine IR
slide 38 of 55
    

Morphine Sulfate ER

slide 39 of 55, Morphine Sulfate ER,

100 mg/12 hours, round, imprinted with 100, ABG

Image of Morphine Sulfate ER
slide 39 of 55
    

Morphine Sulfate ER

slide 40 of 55, Morphine Sulfate ER,

15 mg/12 hr, round, imprinted with 15, ABG

Image of Morphine Sulfate ER
slide 40 of 55
    

Morphine Sulfate ER

slide 41 of 55, Morphine Sulfate ER,

30 mg/12 hr, round, purple, imprinted with 30, ABG

Image of Morphine Sulfate ER
slide 41 of 55
    

Morphine Sulfate ER

slide 42 of 55, Morphine Sulfate ER,

60 mg/12 hours, round, imprinted with 60, ABG

Image of Morphine Sulfate ER
slide 42 of 55
    

Morphine Sulfate ER

slide 43 of 55, Morphine Sulfate ER,

100 mg/12 to 24 hr, capsule, green, imprinted with UPSHER-SMITH 0233, 100 mg

Image of Morphine Sulfate ER
slide 43 of 55
    

Morphine Sulfate ER

slide 44 of 55, Morphine Sulfate ER,

20 mg/12 to 24 hr, capsule, yellow, imprinted with UPSHIRE-SMITH 0226, 20 mg

Image of Morphine Sulfate ER
slide 44 of 55
    

Morphine Sulfate ER

slide 45 of 55, Morphine Sulfate ER,

30 mg/12 to 24 hr, capsule, purple, imprinted with UPSHER-SMITH 0227, 30 mg

Image of Morphine Sulfate ER
slide 45 of 55
    

Morphine Sulfate ER

slide 46 of 55, Morphine Sulfate ER,

60 mg/12 to 24 hr, capsule, pink, imprinted with UPSHER-SMITH 0229, 60 mg

Image of Morphine Sulfate ER
slide 46 of 55
    

MS Contin

slide 47 of 55, MS Contin,

100 mg/12 hours, round, gray, imprinted with PF, 100

Image of MS Contin
slide 47 of 55
    

MS Contin

slide 48 of 55, MS Contin,

15 mg/12 hr, round, blue, imprinted with M 15, PF

Image of MS Contin
slide 48 of 55
    

MS Contin

slide 49 of 55, MS Contin,

30 mg/12 hr, round, pink, imprinted with PF, M 30

Image of MS Contin
slide 49 of 55
    

MS Contin

slide 50 of 55, MS Contin,

60 mg/12 hours, round, beige, imprinted with PF, M 60

Image of MS Contin
slide 50 of 55
    

Oramorph SR

slide 51 of 55, Oramorph SR,

15 mg/12 hr, round, white, imprinted with 54 782, 15

Image of Oramorph SR
slide 51 of 55
    

Oramorph SR

slide 52 of 55, Oramorph SR,

100 mg/12 hours, round, white, imprinted with 54 862, 100

Image of Oramorph SR
slide 52 of 55
    

Oramorph SR

slide 53 of 55, Oramorph SR,

15 mg/12 hr, round, white, imprinted with 54 782, 15

Image of Oramorph SR
slide 53 of 55
    

Oramorph SR

slide 54 of 55, Oramorph SR,

30 mg/12 hr, round, white, imprinted with 54 409, 30

Image of Oramorph SR
slide 54 of 55
    

Oramorph SR

slide 55 of 55, Oramorph SR,

60 mg/12 hours, round, white, imprinted with 54 933, 60

Image of Oramorph SR
slide 55 of 55
    

What is the most important information I should know about morphine?

You should not take this medicine if you have severe asthma or breathing problems, a blockage in your stomach or intestines, or a bowel obstruction called paralytic ileus.

Morphine can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

Taking this medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn.

Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.

What is morphine?

Morphine is an opioid pain medication, sometimes called a narcotic.

Morphine is used to treat moderate to severe pain. Short-acting morphine is taken as needed for pain.

The extended-release form of morphine is for around-the-clock treatment of pain. This form of morphine is not for use on an as-needed basis for pain.

Morphine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using morphine?

You should not take this medicine if you have ever had an allergic reaction to morphine or other narcotic medicines, or if you have:

  • severe asthma or breathing problems; or
  • a blockage in your stomach or intestines.

Do not use morphine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

To make sure morphine is safe for you, tell your doctor if you have ever had:

  • any type of breathing problem or lung disease;
  • a head injury, brain tumor, or seizures;
  • a drug or alcohol addiction, or mental illness;
  • urination problems;
  • liver or kidney disease; or
  • problems with your gallbladder, pancreas, or thyroid.

Some medicines can interact with morphine and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

If you use morphine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

Do not breast-feed while taking morphine. This medicine can pass into breast milk and cause drowsiness, breathing problems, or death in a nursing baby.

How should I use morphine?

Follow all directions on your prescription label. Morphine can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never use morphine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Morphine may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away morphine is against the law.

Stop taking all other around-the-clock narcotic pain medications when you start taking morphine.

Do not crush, chew, or break an extended-release tablet. Swallow it whole to avoid exposure to a potentially fatal dose.

To make swallowing easier, you may open the extended-release capsule and sprinkle the medicine into a spoonful of applesauce. Swallow right away without chewing. Do not save the mixture for later use.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not stop using morphine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using morphine.

Never crush or break a morphine pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death with the misuse of morphine and similar prescription drugs.

Store at room temperature, away from heat, moisture, and light. Keep track of your medicine. Morphine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Do not keep leftover opioid medication. Just one dose can cause death in someone using this medicine accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush the unused medicine down the toilet.

What happens if I miss a dose?

Morphine is sometimes taken only once per day, and sometimes 2 or 3 times per day. Since morphine is used for pain, you are not likely to miss a dose. If you do miss a dose, take the medicine as soon as you remember. Then take your next dose as follows:

  • If you take morphine 3 times per day: Take your next dose 8 hours after taking the missed dose.
  • If you take morphine 2 times per day: Take your next dose 12 hours after taking the missed dose.
  • If you take morphine 1 time per day: Take your next dose 24 hours after taking the missed dose.

Do not take extra medicine to make up a missed dose. Do not take more than your prescribed dose in a 24-hour period.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A morphine overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, very slow breathing, or coma.

What should I avoid while using morphine?

Do not drink alcohol. Dangerous side effects or death could occur.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how morphine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

What are the possible side effects of morphine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other opioid medicines, morphine can slow your breathing. Death may occur if breathing becomes too weak. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Call your doctor at once if you have:

  • slow heart rate, sighing, weak or shallow breathing;
  • chest pain, fast or pounding heartbeats;
  • extreme drowsiness, feeling like you might pass out; or
  • low cortisol levels -- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Serious side effects may be more likely in older adults and those who are malnourished or debilitated.

Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.

Common side effects may include:

  • drowsiness, dizziness;
  • constipation, stomach pain, nausea, vomiting;
  • headache, tired feeling;
  • anxiety; or
  • mild itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect morphine?

Narcotic (opioid) medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:

  • other narcotic medications --opioid pain medicine or prescription cough medicine;
  • a sedative like Valium --diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others; or
  • drugs that make you sleepy or slow your breathing --a sleeping pill, muscle relaxer, tranquilizer, antidepressant, or antipsychotic medicine.

This list is not complete. Other drugs may interact with morphine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about morphine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2018 Cerner Multum, Inc. Version: 13.01. Revision date: 12/12/2017.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.